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KMID : 0043319920150030239
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Archives of Pharmacal Research
1992 Volume.15 No. 3 p.239 ~ p.241
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The Antibacterial Component from Cinnamomi Cortex against a Cariogenic Bacterium Streptococcus mutans OMZ 176
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Bae KH
Ji JM/Park KL
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Abstract
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The methanol extract of Cinnamomi Cortex showed antibacterial action against cariogenic bacterium, Streptococcus mutans OMZ 176. The active principle of the extract was identified to be trans-cinnamaldehyde, which was bactericidal in the minimal inhibitory concentration (MIC) of 100mcg/ml against the strain. From the results of antibacterial activity of cinnamaldehyde and its derivatives, the acrolein group in the cinnamaldehyde was elucidated to be an essential element for the activity.
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